Inducing Cervical Ripening

Informing HCPs and guiding them to successful labor induction

What did the client need?

The client needed to reach health care practitioners and introduce the new mode of release of an existing active agent used for cervical ripening. The basis for the new delivery mode was a vaginal insert with an elaborate matrix that encloses the drug, in this case a prostaglandin E1 analog. The client also chose to depict the manufacturing process of the vaginal insert to highlight the matrix’s unique structure and to further underline the effectiveness of the new mode of release. Additionally, the film had to contain a step-by-step instructional application video for health care practitioners. Finally, the film should compare the product with another insert that contains prostaglandin E2; the advantages of this agent compared to other market leaders should then become obvious.

How did we meet this need?

We developed a 5-minute film that explains the importance of cervical ripening for a successful delivery and shows how this process can be pharmacologically assisted with a vaginal insert that delivers the active ingredient. The localization of the cervix is shown with the help of a 3D model of a pregnant female. Zooming into the cervix further reveals the histological changes induced by cervical ripening. As the film targets professionals in the field of gynecology, we strove to illustrate the cervix as accurately as possible regarding size and tissue composition. Subsequently, the film presents the manufacturing process of the vaginal insert to draw attention to the elaborate matrix. This matrix, once dried, traps the active ingredient and releases it in a sustained manner once it is brought into a moist environment such as the vagina. The film ends with a split screen comparing the performance of our client’s insert (with prostaglandin E1) with an insert containing a different active ingredient (prostaglandin E2).

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